Polymer photo-curing dental composition with prolonged antimicrobial action
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D. Mendeleev University of Chemical Technology of Russia, Moscow, Russia
Publication date: 2021-09-27
Public Health Toxicol 2021;1(Supplement Supplement 1):A31

Dental fluoride compositions are of significant interest for the treatment of caries. This is due to the fact that the fluoride ion, released from the composition, is able to inhibit the enzymes of cariogenic bacteria, as well as reduce the demineralization of enamel by forming a protective layer on its surface. However, various fluoride-containing additives can be released from restorative materials and entered the human body orally or by resorption in oral mucosa, which can cause intoxication of the surrounding tissues and the body as a whole.
In this work, a fluorine-containing photo-curable dental composition based on bisphenol A-glycidyl methacrylate, triethylene glycol dimethacrylate and a fluorine-containing modifier, representing fluorocyclotriphosphazene, also containing 4-allyl-2-methoxyphenoxy groups, was obtained. The presence of fluorine in the modifier provides an antimicrobial effect, and due to the allylic groups, phosphazene is embedded in the polymer matrix during copolymerization with acrylates, so it doesn’t wash out of the composite and doesn’t penetrate into the human body.
During the study of the properties of the modified compositions, it was found that they have a prolonged antimicrobial effect in relation to the oral microflora. In addition, mechanical properties such as microhardness, compressive and flexural strength are not deteriorated when modifying the compositions with phosphazene. The resulting composition is proposed to be used as a restorative dental material, in particular, for the manufacture of photo-curing fillings.
The work was supported by Mendeleev University of Chemical Technology of Russia. Project Number 2020‐014.
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