Study of diagrams of the phase state of the PVA-water system in a wide range of temperatures and compositions
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Department of Biomaterials, Mendeleev University of Chemical Technology of Russia, Moscow, Russia
Laboratory of structural and morphological investigations, Frumkin Institute of Physical chemistry and Electrochemistry RAS, Moscow, Russia
Publication date: 2021-09-27
Public Health Toxicol 2021;1(Supplement 1):A27
Polyvinyl alcohol is a synthetic polymer that is widely used in industry for commercial, medical, and food applications. Crosslinked PVA can be used as high porosity hydrogels due to the network structure of crosslinked polymer chains that induces molecular diffusion1. Small molecules (eg peptides, proteins) can diffuse in and out of the matrix, while larger molecules (eg plasmid DNA) often enter the pores and become trapped within the mesh. This property makes it possible to use crosslinked PVA as porous hydrogel filter systems. In this regard, we are faced with the task of obtaining composite porous filtration systems that allow multiple contact of the air mass with the biocidal surface formed in these systems intended for disinfection.
At this stage, a diagram of the phase state of the PVA - water system was constructed in a wide range of temperatures and compositions, from which it can be seen that the phase equilibrium in the PVA - water system is characterized by a complex amorphous-crystalline equilibrium.
It has been established that for the formation of porous hydrophilic sorbents with a predominantly binding and stable pore system under conditions of prolonged operation in humid environments, it is necessary - (1) to carry out the process of structure formation in the PVA region, solutions in water corresponding to the location of the water liquidus line on the phase state diagram; (2) a network of chemical bonds should be created in the dispersed phase of the sorbent, which can then be used to regulate and stabilize the hydrophilic properties of the sorbent during its operation and regeneration.
This work was supported by Russian Foundation to Basic Research 18-29-18039.
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